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FXR1 RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local translation of certain mRNAs. Interacts with FMR1 and FXR2. Interacts with TDRD3, and with CYFIP2 but not with CYFIP1. Expressed in all tissues examined including heart, brain, kidney and testis. Belongs to the FMR1 family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: RNA-binding; Translation
Chromosomal Location of Human Ortholog: 3q26.33
Cellular Component: cytoplasm; cytosol; membrane; nucleolus; polysome
Molecular Function: mRNA binding; protein binding; protein heterodimerization activity; protein homodimerization activity; RNA binding; RNA strand annealing activity
Biological Process: apoptosis
Reference #:  P51114 (UniProtKB)
Alt. Names/Synonyms: Fragile X mental retardation syndrome-related protein 1; fragile X mental retardation, autosomal homolog 1; FXR1; hFXR1p
Gene Symbols: FXR1
Molecular weight: 69,721 Da
Basal Isoelectric point: 5.84  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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