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CD63 This antigen is associated with early stages of melanoma tumor progression. May play a role in growth regulation. Belongs to the tetraspanin (TM4SF) family. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 12q13.2
Cellular Component: cell surface; endosome membrane; extracellular space; integral component of plasma membrane; intrinsic component of plasma membrane; late endosome membrane; lysosomal membrane; melanosome; plasma membrane; platelet dense granule membrane
Molecular Function: protein binding
Biological Process: cell migration; cell-matrix adhesion; neutrophil degranulation; pigment granule maturation; platelet degranulation; positive regulation of receptor internalization; protein transport
Reference #:  P08962 (UniProtKB)
Alt. Names/Synonyms: CD63; CD63 antigen; CD63 antigen (melanoma 1 antigen); CD63 molecule; Granulophysin; LAMP-3; Lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3; ME491; melanoma 1 antigen; Melanoma-associated antigen ME491; melanoma-associated antigen MLA1; MLA1; Ocular melanoma-associated antigen; OMA81H; Tetraspanin-30; Tspan-30; TSPAN30
Gene Symbols: CD63
Molecular weight: 25,637 Da
Basal Isoelectric point: 8.14  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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