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EML4 a microtubule-associated protein. A WD-repeat protein associated with the mitotic spindle apparatus. May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic. Strongly overexpressed during mitosis. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 2p21
Cellular Component: membrane; microtubule cytoskeleton
Molecular Function: microtubule binding
Reference #:  Q9HC35 (UniProtKB)
Alt. Names/Synonyms: C2orf2; DKFZp686P18118; echinoderm microtubule associated protein like 4; Echinoderm microtubule-associated protein-like 4; ELP120; EMAL4; EMAP-4; EMAPL4; EML4; FLJ10942; FLJ32318; Restrictedly overexpressed proliferation-associated protein; Ropp 120; ROPP120
Gene Symbols: EML4
Molecular weight: 108,916 Da
Basal Isoelectric point: 5.96  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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