an ubiquitous histone acetyltransferase that promotes transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. Has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. Interacts with P300, CBP, ADA2, and is a component of the TFTC-HAT complex. Two splice variant isoforms have been described. Note: This description may include information from UniProtKB.
Biological Process: chromatin remodeling; histone deubiquitination; positive regulation of gene expression, epigenetic; protein deubiquitination; regulation of protein stability; regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter