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RAB11B GTPase that modulates endosomal trafficking. Acts as a major regulator of membrane delivery during cytokinesis. Interacts with RAB11FIP1, RAB11FIP2, RAB11FIP3 and RAB11FIP4. Belongs to the small GTPase superfamily. Rab family. Note: This description may include information from UniProtKB.
Protein type: G protein; G protein, monomeric; G protein, monomeric, Rab
Chromosomal Location of Human Ortholog: 19p13.2
Cellular Component: cytosol; phagocytic vesicle; recycling endosome; recycling endosome membrane; synaptic vesicle
Molecular Function: cadherin binding; GDP binding; GTP binding; GTPase activity; myosin V binding; protein binding
Biological Process: constitutive secretory pathway; melanosome transport; post-translational protein modification; receptor recycling; regulated secretory pathway; transcytosis; transferrin transport
Reference #:  Q15907 (UniProtKB)
Alt. Names/Synonyms: GTP-binding protein YPT3; H-YPT3; MGC133246; RAB11B; RAB11B, member of RAS oncogene family; RAB11B, member RAS oncogene family; Ras-related protein Rab-11B; RB11B; YPT3
Gene Symbols: RAB11B
Molecular weight: 24,489 Da
Basal Isoelectric point: 5.64  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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