Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
Home | Login
About PhosphoSiteUsing PhosphoSiteprivacy & cookiesCuration ProcessContact
logos LINCs Logo Mt Sinai Logo NIH Logo NCI Logo
Search / Browse Functions
Protein Page:

ALDOA a glycolytic enzyme that catalyzes D-fructose 1,6-bisphosphate -> glycerone phosphate + D-glyceraldehyde 3-phosphate. Three forms of aldolase are found in vertebrates - aldolase A in muscle, aldolase B in liver and aldolase C in brain. Note: This description may include information from UniProtKB.
Protein type: Carbohydrate Metabolism - fructose and mannose; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - pentose phosphate pathway; EC; Lyase; Mitochondrial
Chromosomal Location of Human Ortholog: 16p11.2
Cellular Component: actin cytoskeleton; cytosol; extracellular region; extracellular space; I band; membrane; nucleus
Molecular Function: actin binding; cadherin binding; cytoskeletal protein binding; fructose-bisphosphate aldolase activity; identical protein binding; protein binding; RNA binding; tubulin binding
Biological Process: actin filament organization; ATP biosynthetic process; fructose 1,6-bisphosphate metabolic process; fructose metabolic process; gluconeogenesis; glycolysis; muscle maintenance; neutrophil degranulation; platelet degranulation; protein homotetramerization; regulation of cell shape; striated muscle contraction
Disease: Glycogen Storage Disease Xii
Reference #:  P04075 (UniProtKB)
Alt. Names/Synonyms: ALDA; ALDOA; aldolase A, fructose-bisphosphate; fructose-1,6-bisphosphate triosephosphate-lyase; Fructose-bisphosphate aldolase A; GSD12; Lung cancer antigen NY-LU-1; MGC10942; MGC17716; MGC17767; Muscle-type aldolase
Gene Symbols: ALDOA
Molecular weight: 39,420 Da
Basal Isoelectric point: 8.3  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below


Protein Structure Not Found.
Download PyMol Script
Download ChimeraX Script

STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Scansite  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein