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LDH-A Homotetramer. Belongs to the LDH/MDH superfamily. LDH family. 5 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Amino Acid Metabolism - cysteine and methionine; Apoptosis; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - propanoate; Carbohydrate Metabolism - pyruvate; EC; Oxidoreductase
Chromosomal Location of Human Ortholog: 11p15.1
Cellular Component: cytosol; membrane; nucleus
Molecular Function: cadherin binding; L-lactate dehydrogenase activity; protein binding
Biological Process: pyruvate metabolic process
Disease: Glycogen Storage Disease Xi
Reference #:  P00338 (UniProtKB)
Alt. Names/Synonyms: cell proliferation-inducing gene 19 protein; GSD11; L-lactate dehydrogenase A chain; lactate dehydrogenase A; lactate dehydrogenase M; LDH muscle subunit; LDH-A; LDH-M; LDH1; LDHA; LDHM; PIG19; proliferation-inducing gene 19; Renal carcinoma antigen NY-REN-59
Gene Symbols: LDHA
Molecular weight: 36,689 Da
Basal Isoelectric point: 8.44  Predict pI for various phosphorylation states
CST Pathways:  Warburg Effect
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.
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