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P2Y2 a G-protein coupled receptor of the rhodopsin family. This family includes hormone, neurotransmitter and light receptors. Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylthio-ATP = ADP. May participate in control of the cell cycle and proliferation. Note: This description may include information from UniProtKB.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; Receptor, misc.
Chromosomal Location of Human Ortholog: 11q13.4
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: receptor activity
Biological Process: cellular ion homeostasis
Reference #:  P41231 (UniProtKB)
Alt. Names/Synonyms: HP2U; MGC20088; MGC40010; P2RU1; P2RY2; P2U; P2U nucleotide receptor; P2U purinoceptor 1; P2U1; P2UR; P2Y purinoceptor 2; P2Y2; P2Y2R; purinergic receptor P2Y, G-protein coupled, 2; purinergic receptor P2Y2; purinoceptor P2Y2
Gene Symbols: P2RY2
Molecular weight: 42,273 Da
Basal Isoelectric point: 9.72  Predict pI for various phosphorylation states
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