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Protein Page:

NCL the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and preribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-RNA transcription and ribosome assembly. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Helicase; Nuclear receptor co-regulator; Nucleolus; RNA-binding
Chromosomal Location of Human Ortholog: 2q37.1
Cellular Component: cell cortex; membrane; nucleolus; nucleoplasm; nucleus; ribonucleoprotein complex
Molecular Function: identical protein binding; mRNA 5'-UTR binding; protein binding; protein C-terminus binding; RNA binding; telomeric DNA binding
Biological Process: angiogenesis; negative regulation of translation
Reference #:  P19338 (UniProtKB)
Alt. Names/Synonyms: C23; FLJ45706; FLJ59041; NCL; NUCL; Nucleolin; Protein C23
Gene Symbols: NCL
Molecular weight: 76,614 Da
Basal Isoelectric point: 4.6  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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