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Protein Page:

FAM129B a maternal imprinting gene. Absent in pituitary adenomas. May possess growth suppressor activity. Two major alternatively spliced isoforms have been described. forms. One form, Meg3-proximal ( Meg3p), contains exons 1-3. The second form, Meg3-distal ( Meg3d) did not contain exons 1-3 and was present in oocytes and in 1- and 2-cell embryos. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion
Chromosomal Location of Human Ortholog: 9q34.11
Cellular Component: adherens junction; cytoplasm; cytosol; nucleoplasm; nucleus; plasma membrane
Molecular Function: cadherin binding; transcription coactivator activity
Biological Process: axon guidance; cell differentiation; gonadotropin secretion; negative regulation of angiogenesis; negative regulation of apoptosis; negative regulation of cell proliferation; negative regulation of Notch signaling pathway; negative regulation of transcription, DNA-dependent; negative regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of embryonic development; positive regulation of skeletal muscle fiber development; positive regulation of transcription, DNA-dependent
Reference #:  Q96TA1 (UniProtKB)
Alt. Names/Synonyms: bA356B19.6; C9orf88; DKFZP434H0820; FAM129B; family with sequence similarity 129, member B; FLJ13518; FLJ22151; FLJ22298; Meg-3; MINERVA; Niban-like protein 1; NIBL1; OC58; Protein FAM129B
Gene Symbols: FAM129B
Molecular weight: 84,138 Da
Basal Isoelectric point: 5.82  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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