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ATG3 an E2-like enzyme essential for Apg8p lipidation. Note: This description may include information from UniProtKB.
Protein type: Autophagy; EC 6.3.2.-; Ubiquitin conjugating system
Chromosomal Location of Human Ortholog: 3q13.2
Cellular Component: cytoplasmic ubiquitin ligase complex; cytosol
Molecular Function: APG12 conjugating enzyme activity; APG8 conjugating enzyme activity; enzyme binding; protein binding; small conjugating protein ligase activity
Biological Process: autophagic vacuole formation; macroautophagy; mitochondrial fragmentation during apoptosis; mitochondrion degradation; protein modification process; protein targeting to membrane; protein ubiquitination
Reference #:  Q9NT62 (UniProtKB)
Alt. Names/Synonyms: 2610016C12Rik; APG3; APG3 autophagy 3-like; APG3-like; APG3L; ATG3; ATG3 autophagy related 3 homolog (S. cerevisiae); autophagy Apg3p/Aut1p-like; Autophagy-related protein 3; DKFZp564M1178; FLJ22125; hApg3; MGC15201; PC3-96; Protein PC3-96
Gene Symbols: ATG3
Molecular weight: 35,864 Da
Basal Isoelectric point: 4.66  Predict pI for various phosphorylation states
CST Pathways:  Autophagy Signaling
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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