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Protein Page:

ENO1 an abundant cytoplasmic enzyme with 2-phospho-D-glycerate hydro-lyase activity. A target of excess protein nitration in Alzheimer disease (AD) brain. Tau-crystallin, a structural lens protein, is produced from an alternative translation start in the enolase gene. Note: This description may include information from UniProtKB.
Protein type: Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC; Lyase; Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 1p36.23
Cellular Component: cell surface; cytoplasm; cytosol; extracellular space; membrane; nucleus; phosphopyruvate hydratase complex; plasma membrane
Molecular Function: cadherin binding; GTPase binding; phosphopyruvate hydratase activity; protein binding; protein homodimerization activity; RNA binding
Biological Process: gluconeogenesis; negative regulation of cell growth; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of muscle contraction; response to virus
Reference #:  P06733 (UniProtKB)
Alt. Names/Synonyms: 2-phospho-D-glycerate hydro-lyase; alpha enolase like 1; Alpha-enolase; C-myc promoter-binding protein; ENO1; ENO1L1; ENOA; Enolase 1; enolase 1, (alpha); MBP-1; MBPB1; MPB-1; MPB1; MYC promoter-binding protein 1; NNE; Non-neural enolase; Phosphopyruvate hydratase; Plasminogen-binding protein; PPH; tau-crystallin
Gene Symbols: ENO1
Molecular weight: 47,169 Da
Basal Isoelectric point: 7.01  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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