a T cell surface glycoprotein that is a component of the T cell antigen receptor. The recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation. Contains 1 immunoglobulin-like domain and 1 ITAM domain. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Receptor, misc.
Cellular Component: external side of plasma membrane; plasma membrane; T cell receptor complex
Molecular Function: protein binding; protein heterodimerization activity; protein homodimerization activity; receptor signaling protein activity; SH3 domain binding
Biological Process: G-protein coupled receptor protein signaling pathway; positive regulation of T cell proliferation; protein homooligomerization; regulation of immune response; signal complex assembly; T cell costimulation; T cell receptor signaling pathway; transmembrane receptor protein tyrosine kinase signaling pathway