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CHD-1 a sequence-selective DNA-binding protein. Contains two chromo (chromatin organization modifier) domains and one SNF2-related helicase and ATPase domains. May play an important role in gene regulation. Note: This description may include information from UniProtKB.
Protein type: EC; Helicase
Chromosomal Location of Human Ortholog: 5q15-q21.1
Cellular Component: cytoplasm; fibrillar center; nucleus
Molecular Function: ATP-dependent DNA helicase activity; methylated histone residue binding; protein binding
Biological Process: regulation of transcription from RNA polymerase II promoter
Reference #:  O14646 (UniProtKB)
Alt. Names/Synonyms: ATP-dependent helicase CHD1; CHD-1; CHD1; chromodomain helicase DNA binding protein 1; Chromodomain-helicase-DNA-binding protein 1; DKFZp686E2337
Gene Symbols: CHD1
Molecular weight: 196,688 Da
Basal Isoelectric point: 6.68  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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