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INDO Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen. Belongs to the indoleamine 2,3-dioxygenase family. Note: This description may include information from UniProtKB.
Protein type: Amino Acid Metabolism - tryptophan; Cell cycle regulation; EC; Oxidoreductase
Chromosomal Location of Human Ortholog: 8p11.21
Cellular Component: cytosol
Molecular Function: electron carrier activity; indoleamine 2,3-dioxygenase activity; tryptophan 2,3-dioxygenase activity
Biological Process: female pregnancy; regulation of activated T cell proliferation; tryptophan catabolic process
Reference #:  P14902 (UniProtKB)
Alt. Names/Synonyms: I23O1; IDO; IDO-1; IDO1; INDO; indole 2,3-dioxygenase; Indoleamine 2,3-dioxygenase 1; indoleamine-pyrrole 2,3 dioxygenase; Indoleamine-pyrrole 2,3-dioxygenase
Gene Symbols: IDO1
Molecular weight: 45,326 Da
Basal Isoelectric point: 6.87  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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