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ACTG2 Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Belongs to the actin family. Note: This description may include information from UniProtKB.
Protein type: Contractile; Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 2p13.1
Cellular Component: cytoplasm; cytosol; extracellular space; filopodium; lamellipodium
Biological Process: muscle contraction
Disease: Visceral Myopathy
Reference #:  P63267 (UniProtKB)
Alt. Names/Synonyms: ACTA3; ACTE; ACTG2; ACTH; actin, gamma 2, smooth muscle, enteric; Actin, gamma-enteric smooth muscle; actin-like protein; ACTL3; ACTSG; alpha-actin 3; Alpha-actin-3; Gamma-2-actin; smooth muscle gamma actin; Smooth muscle gamma-actin
Gene Symbols: ACTG2
Molecular weight: 41,877 Da
Basal Isoelectric point: 5.31  Predict pI for various phosphorylation states
CST Pathways:  Death Receptor Signaling
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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