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HSPB8 Displays temperature-dependent chaperone activity. Monomer. Interacts with HSPB1. Interacts with DNAJB6. By 17-beta-estradiol. Predominantly expressed in skeletal muscle and heart. Belongs to the small heat shock protein (HSP20) family. Note: This description may include information from UniProtKB.
Protein type: Heat shock protein
Chromosomal Location of Human Ortholog: 12q24.23
Cellular Component: cytoplasm; cytosol; intracellular; nucleoplasm; nucleus
Molecular Function: identical protein binding; protein binding; protein kinase activity
Disease: Charcot-marie-tooth Disease, Axonal, Type 2l; Neuronopathy, Distal Hereditary Motor, Type Iia
Reference #:  Q9UJY1 (UniProtKB)
Alt. Names/Synonyms: Alpha-crystallin C chain; CMT2L; CRYAC; DHMN2; E2-induced gene 1 protein; E2IG1; H11; heat shock 22kDa protein 8; heat shock 27kDa protein 8; Heat shock protein beta-8; HMN2; HMN2A; HSP22; HSPB8; Protein kinase H11; Small stress protein-like protein HSP22
Gene Symbols: HSPB8
Molecular weight: 21,604 Da
Basal Isoelectric point: Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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