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ASPSCR1 Tethering protein that sequesters GLUT4-containing vesicles in the cytoplasm in the absence of insulin. Modulates the amount of GLUT4 that is available at the cell surface. Interacts with GLUT4. Ubiquitous. Highly expressed in testis, heart, skeletal muscle and pancreas. 4 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, peripheral; Oncoprotein; Vesicle
Chromosomal Location of Human Ortholog: 17q25.3
Cellular Component: intracellular membrane-bound organelle; nucleoplasm; plasma membrane
Molecular Function: protein binding
Biological Process: positive regulation of protein modification process
Disease: Alveolar Soft Part Sarcoma
Reference #:  Q9BZE9 (UniProtKB)
Alt. Names/Synonyms: Alveolar soft part sarcoma chromosomal region candidate gene 1 protein; alveolar soft part sarcoma chromosome region, candidate 1; Alveolar soft part sarcoma locus; ASPC1; ASPCR1; ASPL; ASPS; ASPSCR1; FLJ45380; RCC17; renal cell carcinoma gene on chromosome 17; renal cell carcinoma, papillary, 17; Renal papillary cell carcinoma protein 17; Tether containing UBX domain for GLUT4; TUG; UBX domain protein 9; UBX domain-containing protein 9; UBXD9; UBXN9
Gene Symbols: ASPSCR1
Molecular weight: 60,183 Da
Basal Isoelectric point: 6.23  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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