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Protein Page:

nestin an intermediate filament protein. It is expressed predominantly in stem cells of the central nervous system in the neural tube. Upon terminal neural differentiation, nestin is downregulated and replaced by neurofilaments. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 2q34
Cellular Component: cytoplasm; extracellular matrix; intermediate filament; intermediate filament cytoskeleton
Molecular Function: CCR5 chemokine receptor binding; intermediate filament binding
Biological Process: brain development; cell projection morphogenesis; embryonic camera-type eye development; G2/M transition of mitotic cell cycle; negative regulation of catalytic activity; negative regulation of neuron apoptosis; negative regulation of protein binding; nervous system development; positive regulation of intermediate filament depolymerization; response to drug; response to ionizing radiation; response to nutrient levels
Reference #:  P21263 (UniProtKB)
Alt. Names/Synonyms: Nes; NEST; Nestin
Gene Symbols: Nes
Molecular weight: 208,797 Da
Basal Isoelectric point: 4.3  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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