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Protein Page:

THAP11 Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers. Belongs to the THAP11 family. Interacts (via coiled coil domain) with HCFC1. Note: This description may include information from UniProtKB.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 16q22.1
Cellular Component: intercellular bridge; nucleoplasm
Molecular Function: DNA binding; protein binding; zinc ion binding
Biological Process: negative regulation of transcription from RNA polymerase II promoter
Reference #:  Q96EK4 (UniProtKB)
Alt. Names/Synonyms: CTG-B43a; CTG-B45d; HRIHFB2206; RONIN; THA11; THAP domain containing 11; THAP domain-containing protein 11; THAP11
Gene Symbols: THAP11
Molecular weight: 34,455 Da
Basal Isoelectric point: 9.18  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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