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ATG12 Ubiquitin-like protein required for autophagy. Conjugated to ATG3 and ATG5. Ubiquitous. Belongs to the ATG12 family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Autophagy; Ubiquitin-like modifier
Chromosomal Location of Human Ortholog: 18|18 C
Cellular Component: autophagic vacuole; membrane; pre-autophagosomal structure membrane; protein complex
Molecular Function: APG8 conjugating enzyme activity; protein binding
Biological Process: autophagic vacuole formation; autophagy; C-terminal protein lipidation; mitochondrion degradation
Reference #:  Q9CQY1 (UniProtKB)
Alt. Names/Synonyms: 4931423H11Rik; A330058M13Rik; Apg12; APG12-like; Apg12l; Atg12; Atg12l; autophagy 12-like; autophagy-related 12 (yeast); autophagy-related 12-like; Autophagy-related protein 12
Gene Symbols: Atg12
Molecular weight: 15,207 Da
Basal Isoelectric point: 4.9  Predict pI for various phosphorylation states
CST Pathways:  Autophagy Signaling
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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