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DLK1 May have a role in neuroendocrine differentiation. Monomer. Found within the stromal cells in close contact to the vascular structure of placental villi, yolk sac, fetal liver, adrenal cortex and pancreas and in the beta cells of the islets of Langerhans in the adult pancreas. Found also in some forms of neuroendocrine lung tumor tissue. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 14q32.2
Cellular Component: extracellular space
Biological Process: negative regulation of Notch signaling pathway
Reference #:  P80370 (UniProtKB)
Alt. Names/Synonyms: delta-like 1 homolog (Drosophila); DLK; DLK-1; DLK1; FA1; Fetal antigen 1; pG2; preadipocyte factor 1; Pref-1; PREF1; Protein delta homolog 1; secredeltin; ZOG
Gene Symbols: DLK1
Molecular weight: 41,300 Da
Basal Isoelectric point: 5.43  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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