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ANXA7 Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. Interacts with PDCD6. Isoform 1 is expressed in brain, heart and skeletal muscle. Isoform 2 is more abundant in liver, lung, kidney, spleen, fibroblasts and placenta. Belongs to the annexin family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Calcium-binding; Lipid-binding; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 10q22.2
Cellular Component: endoplasmic reticulum membrane; membrane; nucleus
Molecular Function: calcium-dependent protein binding; integrin binding; protein binding; RNA binding
Biological Process: autophagy; epithelial cell differentiation; social behavior
Reference #:  P20073 (UniProtKB)
Alt. Names/Synonyms: Annexin A7; Annexin VII; Annexin-7; ANX7; ANXA7; SNX; Synexin
Gene Symbols: ANXA7
Molecular weight: 52,739 Da
Basal Isoelectric point: 5.52  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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