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SLC17A6 Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family
Chromosomal Location of Human Ortholog: 11p14.3
Cellular Component: integral to membrane; synaptic vesicle membrane
Molecular Function: L-glutamate transmembrane transporter activity
Biological Process: ion transport
Reference #:  Q9P2U8 (UniProtKB)
Alt. Names/Synonyms: Differentiation-associated BNPI; Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter; differentiation-associated Na-dependent inorganic phosphate cotransporter; DNPI; SLC17A6; solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6; Solute carrier family 17 member 6; Vesicular glutamate transporter 2; VGLU2; VGLUT2
Gene Symbols: SLC17A6
Molecular weight: 64,392 Da
Basal Isoelectric point: 6.62  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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