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GAD2 Catalyzes the production of GABA. Homodimer. Belongs to the group II decarboxylase family. Note: This description may include information from UniProtKB.
Protein type: Amino Acid Metabolism - alanine, aspartate and glutamate; Carbohydrate Metabolism - butanoate; EC; Lyase; Other Amino Acids Metabolism - beta-alanine; Other Amino Acids Metabolism - taurine and hypotaurine
Chromosomal Location of Human Ortholog: 10p12.1
Cellular Component: plasma membrane
Molecular Function: glutamate decarboxylase activity; protein binding
Biological Process: neurotransmitter secretion; synaptic transmission
Reference #:  Q05329 (UniProtKB)
Alt. Names/Synonyms: 65 kDa glutamic acid decarboxylase; DCE2; GAD-65; GAD2; GAD65; Glutamate decarboxylase 2; glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa); Glutamate decarboxylase 65 kDa isoform; Glutamate decarboxylase-2 (pancreas); MGC161605; MGC161607
Gene Symbols: GAD2
Molecular weight: 65,411 Da
Basal Isoelectric point: 6.45  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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