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THY1 May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Membrane protein, GPI anchor; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 11q23.3
Cellular Component: anchored to external side of plasma membrane; apical plasma membrane; axolemma; cell surface; dendrite; endoplasmic reticulum; external side of plasma membrane; extracellular region; focal adhesion; growth cone; integral to plasma membrane; lipid raft; myelin sheath; plasma membrane
Molecular Function: GTPase activator activity; integrin binding; protein binding; protein kinase binding
Biological Process: angiogenesis; C-terminal protein lipidation; cell-cell adhesion; cell-cell signaling; cytoskeleton organization and biogenesis; focal adhesion formation; integrin-mediated signaling pathway; negative regulation of axonogenesis; negative regulation of cell migration; negative regulation of protein kinase activity; negative regulation of T cell receptor signaling pathway; positive regulation of cellular extravasation; positive regulation of focal adhesion formation; positive regulation of GTPase activity; positive regulation of heterotypic cell-cell adhesion; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of T cell activation; receptor clustering; regulation of cell-matrix adhesion; retinal cone cell development; T cell receptor signaling pathway
Reference #:  P04216 (UniProtKB)
Alt. Names/Synonyms: CD90; CDw90; FLJ33325; Thy-1 antigen; Thy-1 cell surface antigen; Thy-1 membrane glycoprotein; Thy-1 T-cell antigen; THY1
Gene Symbols: THY1
Molecular weight: 17,935 Da
Basal Isoelectric point: 8.96  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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