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INPP4B Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4- trisphosphate and inositol 1,4-bisphosphate. Widely expressed with highest levels occurring in the skeletal muscle and heart. Strongly inhibited by inositol hexakisphosphate. Belongs to the inositol 3,4-bisphosphate 4-phosphatase family. Note: This description may include information from UniProtKB.
Protein type: Carbohydrate Metabolism - inositol phosphate; EC; Motility/polarity/chemotaxis; Phosphatase, lipid
Chromosomal Location of Human Ortholog: 4q31.21
Cellular Component: cytoplasm; cytosol
Molecular Function: inositol-1,3,4-trisphosphate 4-phosphatase activity; phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity; protein binding
Biological Process: inositol phosphate metabolic process; phosphatidylinositol biosynthetic process; signal transduction
Reference #:  O15327 (UniProtKB)
Alt. Names/Synonyms: 4-phosphatase II; inositol polyphosphate 4-phosphatase II; Inositol polyphosphate 4-phosphatase type II; inositol polyphosphate-4-phosphatase, type II, 105kDa; INP4B; INPP4B; MGC132014; Type II inositol-3,4-bisphosphate 4-phosphatase
Gene Symbols: INPP4B
Molecular weight: 104,738 Da
Basal Isoelectric point: 5.87  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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