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IL25 Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses. Belongs to the IL-17 family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Cytokine; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 14|14 C2
Molecular Function: cytokine activity; interleukin-17E receptor binding
Biological Process: eosinophil differentiation; inflammatory response; inflammatory response to antigenic stimulus; interleukin-13 production; interleukin-5 production; positive regulation of transcription from RNA polymerase II promoter; response to fungus; response to nematode
Reference #:  Q8VHH8 (UniProtKB)
Alt. Names/Synonyms: Il17e; IL25; Interleukin 25
Gene Symbols: Il25
Molecular weight: 19,210 Da
Basal Isoelectric point: 8.03  Predict pI for various phosphorylation states
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Protein Structure Not Found.

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