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LAMP1 Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis. Belongs to the LAMP family. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 13q34
Cellular Component: cell soma; cytoplasm; cytosol; dendrite; endosome membrane; external side of plasma membrane; integral component of plasma membrane; late endosome; lysosomal membrane; lysosome; melanosome; membrane; multivesicular body; perinuclear region of cytoplasm; plasma membrane; sarcolemma; synaptic vesicle
Molecular Function: enzyme binding; protein binding; protein domain specific binding; viral receptor activity
Biological Process: autophagic cell death; entry of virus into host cell; induction of apoptosis by granzyme; neutrophil degranulation; positive regulation of natural killer cell degranulation; positive regulation of natural killer cell mediated cytotoxicity; protein stabilization
Reference #:  P11279 (UniProtKB)
Alt. Names/Synonyms: CD107 antigen-like family member A; CD107a; LAMP-1; LAMP1; LAMPA; LGP120; lysosomal-associated membrane protein 1; Lysosome-associated membrane glycoprotein 1; Lysosome-associated membrane protein 1
Gene Symbols: LAMP1
Molecular weight: 44,882 Da
Basal Isoelectric point: Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.
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