Acts as a transcriptional activator in the presence of ARNT. Can activate the CME (CNS midline enhancer) element and the expression of the drebrin gene. Note: This description may include information from UniProtKB.
Molecular Function: DNA binding; protein heterodimerization activity
Biological Process: cellular response to stress; learning; long-term memory; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of excitatory postsynaptic membrane potential; regulation of inhibitory postsynaptic membrane potential; regulation of synaptic plasticity; regulation of synaptic transmission, GABAergic; short-term memory; social behavior
Alt. Names/Synonyms: bHLH-PAS type transcription factor NXF; HLH-PAS transcription factor NXF; LE-PAS; Limbic-enhanced PAS protein; neuronal PAS domain protein 4; Neuronal PAS domain-containing protein 4; Neuronal PAS4; Npas4; Nxf