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RECQL5 May have an important role in DNA metabolism. Interacts with TOP3A and TOP3B. Ubiquitous. Belongs to the helicase family. RecQ subfamily. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: DNA repair, damage; EC; Helicase
Chromosomal Location of Human Ortholog: 17q25.1
Cellular Component: chromosome; cytoplasm; cytosol; DNA-directed RNA polymerase II, holoenzyme; nucleus
Molecular Function: ATP-dependent 3'-5' DNA helicase activity; DNA binding; DNA helicase activity; four-way junction helicase activity
Biological Process: chromosome separation; DNA repair; DNA replication; double-strand break repair via homologous recombination; mitotic cell cycle
Reference #:  O94762 (UniProtKB)
Alt. Names/Synonyms: ATP-dependent DNA helicase Q5; DNA helicase, RecQ-like type 5; FLJ90603; RecQ protein 5; RecQ protein-like 5; RECQ5; RECQL5
Gene Symbols: RECQL5
Molecular weight: 108,858 Da
Basal Isoelectric point: 8.86  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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