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ADRM1 Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity. Interacts with PSMD1, ubiquitin and UCHL5. Belongs to the ADRM1 family. Note: This description may include information from UniProtKB.
Protein type: Cell development/differentiation; Proteasome complex
Chromosomal Location of Human Ortholog: 20q13.33
Cellular Component: cytosol; integral to plasma membrane; membrane; nucleoplasm; plasma membrane; proteasome complex
Molecular Function: protease binding; protein binding; ubiquitin binding
Biological Process: proteasome assembly; protein deubiquitination; RNA elongation from RNA polymerase II promoter; ubiquitin-dependent protein catabolic process
Reference #:  Q16186 (UniProtKB)
Alt. Names/Synonyms: 110 kDa cell membrane glycoprotein; adhesion regulating molecule 1; Adhesion-regulating molecule 1; ADRM1; ARM-1; ARM1; GP110; hRpn13; M(r) 110,000 surface antigen; MGC29536; Proteasomal ubiquitin receptor ADRM1; Proteasome regulatory particle non-ATPase 13; regulatory particle non-ATPase 13; Rpn13; Rpn13 homolog
Gene Symbols: ADRM1
Molecular weight: 42,153 Da
Basal Isoelectric point: 4.96  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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