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BCL2L10 Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK. Binds to Bcl-2, Bcl-X and BAX. Interacts with APAF1. Widely expressed in adult tissues. Preferentially expressed in lung, liver and kidney. Belongs to the Bcl-2 family. Note: This description may include information from UniProtKB.
Protein type: Apoptosis; Membrane protein, integral
Chromosomal Location of Human Ortholog: 15q21.2
Cellular Component: cytosol; membrane; mitochondrial outer membrane; mitochondrion
Molecular Function: protein binding; protein heterodimerization activity; protein homodimerization activity
Biological Process: caspase activation; DNA damage response, signal transduction resulting in induction of apoptosis; female gamete generation; negative regulation of apoptosis; spermatogenesis
Reference #:  Q9HD36 (UniProtKB)
Alt. Names/Synonyms: Anti-apoptotic protein NrH; Apoptosis regulator Bcl-B; B2L10; Bcl-2-like protein 10; BCL-B; Bcl2-L-10; BCL2-like 10 (apoptosis facilitator); BCL2L10; BCLB; Boo; Diva; MGC129810; MGC129811
Gene Symbols: BCL2L10
Molecular weight: 21,973 Da
Basal Isoelectric point: 9.63  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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