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FOXK2 Recognizes the core sequence 5'-TAAACA-3'. Binds to NFAT-like motifs (purine-rich) in the IL2 promoter. Also binds to HIV-1 long terminal repeat. May be involved in both positive and negative regulation of important viral and cellular promoter elements. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 17q25.3
Cellular Component: nucleoplasm; nucleus
Molecular Function: magnesium ion binding; protein binding; sequence-specific DNA binding
Biological Process: anatomical structure morphogenesis; cell differentiation; positive regulation of transcription from RNA polymerase II promoter; protein deubiquitination; regulation of transcription from RNA polymerase II promoter
Reference #:  Q01167 (UniProtKB)
Alt. Names/Synonyms: Cellular transcription factor ILF-1; forkhead box K2; Forkhead box protein K2; FOXK1; FOXK2; ILF; ILF-1; ILF1; interleukin enhancer binding factor 1; Interleukin enhancer-binding factor 1
Gene Symbols: FOXK2
Molecular weight: 69,062 Da
Basal Isoelectric point: 9.56  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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