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SESN2 Involved in the reduction of peroxiredoxins. Widely expressed. Belongs to the sestrin family. Note: This description may include information from UniProtKB.
Chromosomal Location of Human Ortholog: 1p35.3
Cellular Component: AMP-activated protein kinase complex; cytoplasm; cytosol; TORC2 complex
Molecular Function: oxidoreductase activity, acting on peroxide as acceptor; protein binding; sulfiredoxin activity
Biological Process: cellular response to amino acid starvation; cellular response to glucose starvation; DNA damage response, signal transduction by p53 class mediator; negative regulation of cell growth; positive regulation of macroautophagy; regulation of protein amino acid phosphorylation
Reference #:  P58004 (UniProtKB)
Alt. Names/Synonyms: DKFZp761M0212; DKFZp761M02121; Hi95; hypoxia induced gene 95; SES2; SESN2; SEST2; sestrin 2; Sestrin-2
Gene Symbols: SESN2
Molecular weight: 54,494 Da
Basal Isoelectric point: 5.57  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.
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