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CASP7 Involved in the activation cascade of caspases responsible for apoptosis execution. Acts downstream of rpr. Cleaves baculovirus p35 and lamin DmO in vitro.
Protein type: Apoptosis; EC; Endoplasmic reticulum; Mitochondrial; Protease
Cellular Component: cytoplasm
Molecular Function: cysteine-type endopeptidase activity
Biological Process: apoptosis; neuron remodeling; nurse cell apoptosis; positive regulation of compound eye retinal cell programmed cell death; programmed cell death; proteolysis; response to X-ray; salivary gland histolysis; spermatid differentiation; sterol regulatory element binding protein cleavage
Reference #:  O01382 (UniProtKB)
Alt. Names/Synonyms: Caspase; Caspase subunit p12; Caspase subunit p21; CG7788; drICE
Gene Symbols: Ice
Molecular weight: 37,363 Da
Basal Isoelectric point: 6.59  Predict pI for various phosphorylation states
CST Pathways:  Apoptosis Regulation  |  Death Receptor Signaling  |  ErbB/HER Signaling  |  Inhibition of Apoptosis
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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