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CD9 Involved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion. Belongs to the tetraspanin (TM4SF) family. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 12p13.31
Cellular Component: apical plasma membrane; external side of plasma membrane; extracellular space; focal adhesion; integral component of plasma membrane; membrane; plasma membrane; platelet alpha granule membrane
Molecular Function: integrin binding; protein binding
Biological Process: brain development; cell adhesion; cell motility; cell surface receptor signaling pathway; fusion of sperm to egg plasma membrane involved in single fertilization; negative regulation of cell proliferation; oligodendrocyte development; paranodal junction assembly; platelet activation; platelet degranulation; receptor internalization; response to water deprivation
Reference #:  P21926 (UniProtKB)
Gene Symbols: CD9
Molecular weight: 25,416 Da
Basal Isoelectric point: 6.8  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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