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ZNF259 May be a signaling molecule that communicates mitogenic signals from the cytoplasm to the nucleus. Binds to the EGF and PDGF receptors. Binds to the elongation factor 1-alpha EF1A. Component of an import snRNP complex composed of KPNB1, SNUPN, SMN1 and ZNF259. Belongs to the ZPR1 family. Note: This description may include information from UniProtKB.
Protein type: Cell cycle regulation; Nucleolus
Chromosomal Location of Human Ortholog: 11q23.3
Cellular Component: axon; Cajal body; cell soma; cytoplasm; growth cone; nucleolus; nucleoplasm; nucleus; perikaryon; SMN complex
Molecular Function: protein binding; translation initiation factor binding
Biological Process: Cajal body organization and biogenesis; cell proliferation; DNA endoreduplication; microtubule cytoskeleton organization and biogenesis; positive regulation of growth; positive regulation of protein import into nucleus; positive regulation of RNA splicing; regulation of myelination; signal transduction; spinal cord development; trophectodermal cell proliferation
Reference #:  O75312 (UniProtKB)
Alt. Names/Synonyms: MGC110983; Zinc finger protein 259; Zinc finger protein ZPR1; ZNF259; ZPR1
Gene Symbols: ZPR1
Molecular weight: 50,925 Da
Basal Isoelectric point: 4.66  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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