Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
Home | Login
About PhosphoSiteUsing PhosphoSiteprivacy & cookiesCuration ProcessContact
logos LINCs Logo Mt Sinai Logo NIH Logo NCI Logo
Search / Browse Functions
Protein Page:

Spink3 Serine protease inhibitor which exhibits anti-trypsin activity. Inhibits the uptake of calcium by spermatozoa. By androgens in adult male sex accessory glands but expressed constitutively in pancreas.
Protein type: Inhibitor
Chromosomal Location of Human Ortholog: 18|18 B3
Cellular Component: acrosome; extracellular space
Molecular Function: protease inhibitor activity; serine-type endopeptidase inhibitor activity
Biological Process: negative regulation of peptidase activity; negative regulation of peptidyl-tyrosine phosphorylation; regulation of acrosome reaction
Reference #:  P09036 (UniProtKB)
Alt. Names/Synonyms: ISK3; prostatic secretory glycoprotein; serine peptidase inhibitor, Kazal type 3; serine protease inhibitor Kazal-type 3; serine protease inhibitor, Kazal type 3; Spink3
Gene Symbols: Spink3
Molecular weight: 8,488 Da
Basal Isoelectric point: 8.26  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below


Protein Structure Not Found.

STRING  |  BioGPS  |  Scansite  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene