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CP110 Necessary for centrosome duplication at different stages of procentriole formation. Collaborates with CEP97, being involved in the suppression of a cilia assembly program. Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: 16p12.3
Cellular Component: centriole; centrosome; cytosol; protein complex
Molecular Function: protein binding
Biological Process: basal body organization and biogenesis; centriole replication; centrosome duplication; G2/M transition of mitotic cell cycle; positive regulation of flagellum biogenesis; protein deubiquitination; regulation of cytokinesis
Reference #:  O43303 (UniProtKB)
Alt. Names/Synonyms: 9738; CE110; Centrosomal protein of 110 kDa; CEP110; CP110; CP110 protein; DKFZp781G1416; KIAA0419
Gene Symbols: CCP110
Molecular weight: 113,424 Da
Basal Isoelectric point: 8.83  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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