Necessary for centrosome duplication at different stages of procentriole formation. Collaborates with CEP97, being involved in the suppression of a cilia assembly program. Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Cellular Component: centriole; centrosome; cytosol; protein complex
Molecular Function: protein binding
Biological Process: basal body organization and biogenesis; centriole replication; centrosome duplication; G2/M transition of mitotic cell cycle; positive regulation of flagellum biogenesis; protein deubiquitination; regulation of cytokinesis