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IL17RA Receptor for IL17A and IL17F. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling. Widely expressed. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Receptor, cytokine
Chromosomal Location of Human Ortholog: 22q11.1
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: interleukin-17 receptor activity; protein binding
Biological Process: positive regulation of interleukin-23 production
Disease: Candidiasis, Familial, 5
Reference #:  Q96F46 (UniProtKB)
Alt. Names/Synonyms: CD217; CDw217; hIL-17R; I17RA; IL-17 receptor A; IL-17RA; IL17R; IL17RA; interleukin 17 receptor A; Interleukin-17 receptor A; MGC10262
Gene Symbols: IL17RA
Molecular weight: 96,122 Da
Basal Isoelectric point: 5.06  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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