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Protein Page:

ACAT2 The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. [provided by RefSeq, Jul 2008]
Protein type: Acetyltransferase; Amino Acid Metabolism - lysine degradation; Amino Acid Metabolism - tryptophan; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Carbohydrate Metabolism - butanoate; Carbohydrate Metabolism - propanoate; Carbohydrate Metabolism - pyruvate; EC; Lipid Metabolism - fatty acid; Lipid Metabolism - synthesis and degradation of ketone bodies; Secondary Metabolites Metabolism - terpenoid backbone biosynthesis
Chromosomal Location of Human Ortholog: 6q25.3
Cellular Component: cytoplasm; cytosol; mitochondrion; nucleolus; nucleus
Molecular Function: acetyl-CoA C-acetyltransferase activity; protein binding
Biological Process: cholesterol biosynthetic process; fatty acid beta-oxidation; lipid metabolic process
Disease: Acetyl-coa Acetyltransferase-2 Deficiency
Reference #:  Q9BWD1 (UniProtKB)
Alt. Names/Synonyms: ACAT2; acetoacetyl Coenzyme A thiolase; Acetyl-CoA acetyltransferase, cytosolic; Acetyl-CoA transferase-like protein; acetyl-Coenzyme A acetyltransferase 2; ACTL; Cytosolic acetoacetyl-CoA thiolase; THIC
Gene Symbols: ACAT2
Molecular weight: 41,351 Da
Basal Isoelectric point: 6.47  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.
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