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CPLX2 Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in synaptic vesicle exocytosis. Also involved in mast cell exocytosis. Belongs to the complexin/synaphin family. Note: This description may include information from UniProtKB.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 5q35.2
Biological Process: positive regulation of synaptic plasticity; regulation of exocytosis; vesicle docking during exocytosis
Reference #:  Q6PUV4 (UniProtKB)
Alt. Names/Synonyms: 921-L; complexin 2; Complexin II; Complexin-2; CPLX2; CPX II; CPX-2; CPX2; Hfb1; MGC138492; synaphin 1; Synaphin-1
Gene Symbols: CPLX2
Molecular weight: 15,394 Da
Basal Isoelectric point: 5.06  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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