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NRBF2 May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro). Interacts with PPARA, PPARD and PPARG. Interacts with RARA, RARG and RXRA in the presence of bound ligand. Detected in keratinocytes, liver and placenta. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Autophagy; Nuclear receptor co-regulator; Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 10q21.3
Cellular Component: cytoplasm; nucleoplasm
Molecular Function: protein binding
Biological Process: autophagy; transcription initiation from RNA polymerase II promoter
Reference #:  Q96F24 (UniProtKB)
Alt. Names/Synonyms: Comodulator of PPAR and RXR; COPR; COPR1; COPR2; DKFZp564C1664; FLJ30395; NRBF-2; NRBF2; nuclear receptor binding factor 2; nuclear receptor binding factor-2; Nuclear receptor-binding factor 2
Gene Symbols: NRBF2
Molecular weight: 32,378 Da
Basal Isoelectric point: 5.61  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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