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Protein Page:
ICAM2

Overview
ICAM2 ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen- specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Belongs to the immunoglobulin superfamily. ICAM family. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Membrane protein, integral
Chromosomal Location of Human Ortholog: 17q23.3
Cellular Component: cleavage furrow; integral component of plasma membrane; membrane; plasma membrane; uropod
Molecular Function: integrin binding
Biological Process: cell adhesion; extracellular matrix organization; regulation of immune response; stimulatory C-type lectin receptor signaling pathway
Reference #:  P13598 (UniProtKB)
Alt. Names/Synonyms: CD102; ICAM-2; ICAM2; Intercellular adhesion molecule 2
Gene Symbols: ICAM2
Molecular weight: 30,654 Da
Basal Isoelectric point: 7.09  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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ICAM2

Protein Structure Not Found.
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