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Protein Page:

CD8B Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. 8 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 2p11.2
Cellular Component: early endosome membrane; integral to plasma membrane; plasma membrane
Molecular Function: protein binding
Biological Process: regulation of defense response to virus by virus; regulation of immune response
Reference #:  P10966 (UniProtKB)
Alt. Names/Synonyms: CD8 antigen, beta polypeptide (p37); CD8 antigen, beta polypeptide 1 (p37); CD8B; CD8b antigen; CD8b molecule; CD8B1; Leu2; Ly3; LYT3; MGC119115; T lymphocyte surface glycoprotein beta chain; T-cell surface glycoprotein CD8 beta chain
Gene Symbols: CD8B
Molecular weight: 23,722 Da
Basal Isoelectric point: 10.03  Predict pI for various phosphorylation states
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