General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II. Associates with TFIID-IIA (DA complex) to form TFIID-IIA- IIB (DAB-complex) which is then recognized by polymerase II. Interacts with the transcription elongation factor TCEA2. Interacts with HIV-1 Vpr. Interacts with GPBP1. Interacts with Epstein-Barr virus EBNA2. Belongs to the TFIIB family. Note: This description may include information from UniProtKB.
Protein type: Acetyltransferase; Nuclear receptor co-regulator; Transcription factor
Molecular Function: protein binding; TATA-binding protein binding; thyroid hormone receptor binding; transcription factor binding
Biological Process: positive regulation of viral transcription; RNA elongation from RNA polymerase II promoter; snRNA transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcriptional preinitiation complex assembly