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STX6 Involved in intracellular vesicle trafficking. Binds EEA1. Interacts with VPS45A. Interacts with MARCH2 and MARCH3. Interacts with GOPC. Identified in a complex containing STX6, STX12, VAMP4 and VTI1A. Belongs to the syntaxin family. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Vesicle
Chromosomal Location of Human Ortholog: 1q25.3
Cellular Component: clathrin-coated vesicle; cytosol; early endosome; Golgi apparatus; Golgi membrane; integral to membrane; nucleoplasm; perinuclear region of cytoplasm; plasma membrane; SNARE complex; trans-Golgi network; trans-Golgi network membrane
Molecular Function: protein binding; SNAP receptor activity; syntaxin binding
Biological Process: endocytic recycling; intracellular protein transport; regulation of protein localization; retrograde transport, endosome to Golgi; vesicle docking; vesicle fusion
Reference #:  O43752 (UniProtKB)
Alt. Names/Synonyms: STX6; syntaxin 6; Syntaxin-6
Gene Symbols: STX6
Molecular weight: 29,176 Da
Basal Isoelectric point: 4.84  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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