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Protein Page:

SYN1 neuronal phosphoprotein which associates with the cytoplasmic surface of synaptic vesicles and binds to the cytoskeleton. May function in the regulation of neurotransmitter release and of axonogenesis and synaptogenesis. Mutations may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Two differentially spiced isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: Xp11.3-p11.23
Cellular Component: synaptic vesicle
Molecular Function: ATP binding; protein binding; protein kinase binding; transporter activity
Biological Process: regulation of neurotransmitter secretion; synaptic transmission
Disease: Epilepsy, X-linked, With Variable Learning Disabilities And Behavior Disorders
Reference #:  P17600 (UniProtKB)
Alt. Names/Synonyms: Brain protein 4.1; SYN1; SYN1a; SYN1b; Synapsin I; Synapsin-1; SYNI
Gene Symbols: SYN1
Molecular weight: 74,111 Da
Basal Isoelectric point: 9.84  Predict pI for various phosphorylation states
CST Pathways:  GPCR Signaling to MAPKs
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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