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Protein Page:

S6 May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA. Belongs to the ribosomal protein S6e family. Note: This description may include information from UniProtKB.
Protein type: Translation
Chromosomal Location of Human Ortholog: 9p22.1
Cellular Component: cell body; cytoplasmic ribonucleoprotein granule; cytosol; dendrite; intracellular ribonucleoprotein complex; membrane; nucleolus; nucleoplasm; nucleus; perinuclear region of cytoplasm; polysome; small ribosomal subunit
Molecular Function: protein binding; protein kinase binding; RNA binding; structural constituent of ribosome
Biological Process: activated T cell apoptosis; erythrocyte development; G1/S transition of mitotic cell cycle; gastrulation; glucose homeostasis; mitotic cell cycle checkpoint; negative regulation of apoptosis; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; oogenesis stage; placenta development; positive regulation of apoptosis; ribosomal small subunit biogenesis and assembly; rRNA processing; SRP-dependent cotranslational protein targeting to membrane; T cell differentiation in thymus; T cell proliferation during immune response; TOR signaling; translation; translational initiation; viral transcription
Reference #:  P62753 (UniProtKB)
Alt. Names/Synonyms: 40S ribosomal protein S6; Phosphoprotein NP33; ribosomal protein S6; RPS6; RS6
Gene Symbols: RPS6
Molecular weight: 28,681 Da
Basal Isoelectric point: 10.85  Predict pI for various phosphorylation states
CST Pathways:  Growth And Differentiation Control by MAPKs  |  PI3K/Akt Signaling  |  Translation: eIF4E and p70S6K
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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